The Pharmacology of Intravenous Opioids

S Whitener, MD McEvoy, SL Shafer, P Flood - Geriatric Anesthesiology, 2018 - Springer
… based on pharmacokinetics, but meperidine will accumulate … we can conclude that
pharmacokinetics of alfentanil does not … any drugs that decrease consciousness (eg, …

A question of time

PJ Pascoe - Veterinary Anaesthesia and Analgesia, 2018 - vaajournal.org
… For example, in humans, the peak effect of alfentanil (partition … Models based on
pharmacokinetics have provided interesting … of induction of anaesthesia in sheep: variable …

Analgesic efficacy and pharmacokinetics of combinations of morphine, dexmedetomidine and maropitant in dogs: a thesis presented in partial fulfilment of the …

SR Karna - 2020 - mro.massey.ac.nz
… of nociceptive stimuli by the brain; the stimuli could be existing or imaginary (Abbracchio
and Reggiani 2013). In summary, pain is a conscious and highly subjective experience, which …

[PDF][PDF] Analgesic efficacy and pharmacokinetics of combinations of morphine, dexmedetomidine and maropitant in dogs

SR Karna - 2020 - mro.massey.ac.nz
… of nociceptive stimuli by the brain; the stimuli could be existing or imaginary (Abbracchio
and Reggiani 2013). In summary, pain is a conscious and highly subjective experience, which …

Low-dose morphine reduces tolerance to central hypovolemia in healthy adults without affecting muscle sympathetic outflow

JC Watso, LN Belval, FA Cimino 3rd… - American Journal …, 2022 - journals.physiology.org
… accelerates hemorrhage-associated hypotension in conscious sheep [intracerebroventricular …
The pharmacodynamics/pharmacokinetics of morphine and morphine metabolites result in …

Pharmacokinetic and pharmacodynamic interactions in anaesthesia. A review of current knowledge and how it can be used to optimize anaesthetic drug …

JP van den Berg, HEM Vereecke… - BJA: British Journal …, 2017 - academic.oup.com
… Generally, in a sheep model, cardiac output is found to be inversely related to arterial and
… of 50% probability for return of consciousness. Midazolam and alfentanil tend to act supra-…

Pharmacokinetics and pharmacodynamics of drugs commonly used in pregnancy and parturition

J Ansari, B Carvalho, SL Shafer… - Anesthesia & …, 2016 - ingentaconnect.com
… The peak concentration of midazolam is reduced after both oral and parenteral administration
… the exception of midazolam is close to 1 (Table 4), making midazolam the preferred drug …

Analgesic and cardiopulmonary effects of epidural romifidine and morphine combination in horses

CC Natalini, SDLA Paes, A da S Polydoro - Journal of Equine Veterinary …, 2021 - Elsevier
… different doses of romifidine combined with morphine in horses. A … 60 μg/kg (R60) combined
with morphine 0.1 mg/kg with a washout … Epidurally administered romifidine and morphine

[HTML][HTML] Pharmacology related to paediatric anaesthesia

M Maheshwari, S Sanwatsarkar… - Indian Journal of …, 2019 - ncbi.nlm.nih.gov
… In a sheep model, cardiac output is found to be inversely … Interaction between propofol and
alfentanil on laryngoscopy … Midazolam offers a better pharmacokinetic profile than diazepam …

Cheyne–Stokes respiration in two sheep during recovery from general anaesthesia for experimental convection enhanced drug delivery

M Cambruzzi, H van Oostrom… - Veterinary Record Case …, 2022 - Wiley Online Library
… vein and the sheep were premedicated with midazolam (Midazolam, … Alterations in the level
of consciousness are associated with … , the pharmacokinetics of alfentanil in sheep has been …